On click of the cell, the name of the cell automatically gets inserted. Press the ‘CTRL’ button and hold it and mouse click the two numbers. Press ‘CTRL’ and Select Two Numbers By Clicking on it You have to place the equals to(=) operator in the cell D4 to start the formula in Excel.Ĭheck the above image contains the equals to(=) operator as the starting point of the calculation.ģ. Now, suppose you have to calculate the difference between these two numbers in the cell D4. Place equals to(=) operator Where you have to Calculate Subtraction The cell is B4 and C4 with B4 contains the largest number and C4 contains the smallest number.Ģ. The above image showing the two number which you want to get the difference as the output. You have to use these numbers to calculate the difference between these two numbers. Put any two numbers in the cell which you want to find the subtraction. Subtract Two Numbers in Excel Using Minus(-) Operator Calculate Difference Between Two Columns in Excel.How To Find Difference of More Than Two Numbers in Excel.Subtract Two Numbers in Excel Using Minus(-) Operator.